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F&C Investment Trust PLC ("the Company") LEI: 213800W6B18ZHTNG7371 Portfolio Update In accordance with Listing Rule 15.6.8 the Company discloses that as at 31 December 2022 it held the following investments in other listed closed-ended investment funds which do not have a stated investment policy to invest no more than 15% of their total assets in other listed closed-ended investment funds: Holding % of the Company's Gross Assets Syncona Limited 0.35 Name of contact and telephone number for enquiries: Jonathan Latter For and on behalf of Columbia Threadneedle Investment Business Limited, Secretary Telephone: 020 7628 8000 4 January 2023 End CA:00404936 For:FCT Type:MKTUPDTE Time:2023-01-05 08:30:11